Cause Ulcers
Mechanisms involved in gluten intolerance:
- Lack of digestive enzymes (intestinal glutaminase)
- Production of anti-prolamin antibodies, or fragments of it.
- Increased intestinal permeability to macromolecules and protein antigens.
- Increased production of mediators (histamine, serotonin, kinins, prostaglandins, and interleukins).
- The first-degree relatives have a predisposition to be found on chromosome 6 and is the most common marker associated with HLA DQw2.
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