Critical Medicine and Treatment

Archive for the ‘Sprue’ Category

Following a diet free of gluten (wheat flour) in two weeks there is an improvement of symptoms in most cases. If no improvement may be that the diet is not suitable or because complications occur lymphoma. In asymptomatic individuals the diet is made also because the disease tends to worsen if nothing is done and because the incidence of lymphomas and adenocarcinomas increases seem to match these tumors increased with the degree of intestinal inflammation. Therefore it is not clear that individuals with positive serology but no intestinal inflammation should take this diet.

Parallel to diarrhea diseases chronic intolerance to gluten. Not always associated with the intestinal disorder.

• Hyperkinetic Syndrome
• Epilepsies
• Disturbances of attention
• Intestinal lymphoma
• Intestinal Adenocarcinomas
• Dermatitis herpetiformis
• Schizophrenia

Diagnosis is made by measuring specific antibodies in the blood, a biopsy of the intestine and symptoms. Duodenal biopsy is often, but will be more sensitive to the jejunum.

Are three different models that vary according to clinical presentation:

Villous epithelial infiltration with lymphocytes, with normal villi and crypts. This model was found in 40% of individuals with Dermatitis Herpetiformis and a small portion of patients with bowel involvement and affected relatives are asymptomatic. Elongation of the crypts and flattening and inflammatory cells in the lamina propria. This model is classically in individuals with celiac disease with intestinal symptoms in asymptomatic affected relatives, and individuals with dermatitis herpetiformis. In most of these individuals, treatment with a gluten-free diet results in improvement of the villi and crypts architecture that becomes normal or nearly normal.

Complete flattening of the mucosa with absence of villi and crypts very small. It is found in more severely affected patients. It is often refractory to gluten-free diet, and the injury is not reversible. Are patients requiring intravenous nutrition supplements. Property and repeated biopsy to avoid false positives of intestinal infections, with lesions caused by lactose. We must also bear in mind that patients in remission or with intermittent symptoms may have normal biopsy and the results of the analysis but remain very sensitive to any prolamin.

Mechanisms involved in gluten intolerance:

• Lack of digestive enzymes (intestinal glutaminase)
• Production of anti-prolamin antibodies, or fragments of it.
• Increased intestinal permeability to macromolecules and protein antigens.
• Increased production of mediators (histamine, serotonin, kinins, prostaglandins, and interleukins).
• The first-degree relatives have a predisposition to be found on chromosome 6 and is the most common marker associated with HLA DQw2.

sprue is a lesion or disorder in the form ulser (ulcers) found in the oral cavity. Ulser disorders have various types, but most often experienced by people is the kind of aphtous stomatitis or Canker Sores. What causes ulcers? What symptoms of ulcers? And how treatment ulcers?
Causes of Sprue
The lesions are usually found on the sprue mucosa of the lips, cheeks, tongue, soft palate, and gum base. The cause of canker sores remains unclear, but many who mentioned the theory that ulcers associated with immune problems.
Several types of disease, lack of intake of nutrients (especially iron and vitamin B12), allergies, trauma (eg being bitten), stress, and hormonal changes (menstrual cycle) can also trigger canker sores.

Sprue Symptoms
Sprue may appear as lesions of small size, large, or in significant amounts. Sprue lesion may also appear repeatedly or phrase is called recurrent.

Before ulser formed lesions, inflamed areas usually stung like a punctured or burned. After 2 or 3 days later ulser lesions formed in the inflamed area.
The pain of small ulcers will usually lost between 7 to 10 days, and these lesions will recover completely within 1 to 2 weeks. However, if the size of the lesions, ulcers large enough lesion usually takes between several weeks to several months to heal.
Sprue who do not recover within 1 week should be consulted with a dentist. Because there are several other diseases more dangerous form similar lesinya sprue, including dangerous diseases such as cancer of the mouth. Read the rest of this entry »